Patent
Alcohol dehydrogenase mutant and application thereof in preparation of high-concentration (S)-glassine.
The invention presents a polyphosphokinase mutant designed to improve the efficiency of the ATP regeneration system. By introducing mutations Y286Stop or L290Stop in the wild-type polyphosphokinase, the mutant exhibits higher activity. When used in a genetically engineered Escherichia coli strain, this mutant catalyzes the synthesis of NMN (nicotinamide mononucleotide) from D-ribose, ATP, and nicotinamide, achieving a high yield of 25.2 g/L in 3 hours, demonstrating significant industrial potential for large-scale NMN production.
Product Tag:
Polyphosphokinase Mutant
Industry Tag:
Synthetic Biology
Method for producing PHA through semi-continuous fermentation
The invention provides a method for producing polyhydroxyalkanoate (PHA) via semi-continuous fermentation using Halomonas as a base strain, with the overexpression of the cell division protein gene ftsZ. This approach addresses the issues of reduced splitting activity and lower yield due to metabolic disturbances during long continuous fermentation, achieving high PHA yields in practical applications, and offering strong potential for industrial scalability.
Pectase-producing microbubble bacteria and application thereof.
The invention discloses a pectinase-producing strain, identified as Microvesicles MYHB-202306PeC, belonging to the Microvesicles genus. This strain is capable of high salt tolerance and the secretion of pectinase, which makes it useful in applications such as food processing, waste management, and other industrial uses requiring pectin degradation.
Exoid sea source bacteria secreting xylanase and application thereof.
The invention discloses a kind of sea source bacteria secreting xylanase and its application, and relates to the field of microbial technology, and the invention discovers a new microbial strain, and the bacteria are identified and confirmed to belong to the genus sea source bacteria, named as sea source bacteria MYHB-202307XyL (Aliidiomarina sp. MYHB-202307 XyL). Experiments prove that the strain has the capability of resisting high salt and secreting xylanase.
Recombinant halomonas and application thereof in recombinant protein production.
This invention presents a recombinant Halomonas strain optimized for recombinant protein production by knocking down flagella genes, significantly enhancing protein yield and offering an efficient strain development method to improve industrial protein production and reduce costs.
Engineered halomonas for producing PHA (polyhydroxyalkanoate) and PHA production method.
The invention involves an engineered Halomonas strain for producing polyhydroxyalkanoate (PHA), which increases PHA yield by reducing the expression of the cytochrome d oxidase compound gene cydA or its protein activity. This modification allows efficient PHA synthesis under low-rotation-speed or even stirring-free anoxic/anaerobic conditions in the later stages of fermentation, significantly reducing energy consumption and offering a cost-effective approach for large-scale PHA production.
Novel amylase Zhuo Beier-producing strain and application thereof.
The invention discloses a new amylase-producing strain of Zobellella, identified as Zobellella sp. MYHB_202302AmY. This strain demonstrates high salt tolerance and the ability to secrete amylase, making it useful in applications such as biotechnological processes for starch degradation, food industries, and other areas requiring amylase activity under extreme conditions.
Novel bacillus deserticola strain capable of producing chitinase and application of novel bacillus deserticola strain.
The invention discloses a novel Bacillus deserticus strain, identified as Bacillus deserticus MYHB202305ChI, which is capable of producing chitinase and has high salt resistance. This strain shows promising potential for applications in biotechnology, particularly in areas requiring chitin degradation, such as pest control and waste management.
Industry leaders use Knowledge Hub to explore 368+ Synthetic Biology Patents
Gain unparalleled insights, and drive your novelty forward.
Let’s shape tomorrow, today!