Patent

Recombinant III type collagen with triple helix structure, and preparation method and application thereof

Recombinant humanized type III collagen with a triple-helix structure, built from low-immunogenic, high-activity fragments, is efficiently expressed in engineered bacteria at high yield.

30 May 2025 | Pending

Product Tag:

Recombinant type VII collagen

Industry Tag:

Cosmetics

Freckle-removing recombinant humanized collagen composition and preparation method and application thereof

A freckle-removing composition with recombinant humanized collagen linked between two functional fragments of type III collagen and histidine, providing low-irritation skin whitening.

26 May 2025 | Pending

Product Tag:

Freckle-removing composition

Industry Tag:

Cosmetics

Recombinant VII type collagen with firming and anti-wrinkle effects

Recombinant type VII collagen with 2–100 repeats of GLPGAKGEKGAP, expressed in Pichia pastoris with up to 17.3 g/L yield, enhances autophagy and delivers anti-wrinkle effects.

10 April 2025 | Pending

Product Tag:

Recombinant type VII collagen

Industry Tag:

Cosmetics

Recombinant collagen capable of enhancing skin regeneration capacity as well as preparation method and application of recombinant collagen

Recombinant type III collagen, engineered from the human ?1 strand gene and produced in Pichia pastoris offers higher yield for skin regeneration and repair.

10 March 2025 | Active

Technology Tag:

Product Tag:

Anti-aging formulation

Industry Tag:

Cosmetics

Recombinant human-derived III-type collagen and preparation method and application thereof

The invention provides recombinant type III collagen with high expression, low toxicity, and biocompatibility produced via a gene expression, applicable in skincare applications.

25 February 2025 | Active

Technology Tag:

Product Tag:

Skincare formulation

Industry Tag:

Cosmetics

Alcohol dehydrogenase mutant and application thereof in preparation of high-concentration (S)-glassine.

The invention presents a polyphosphokinase mutant designed to improve the efficiency of the ATP regeneration system. By introducing mutations Y286Stop or L290Stop in the wild-type polyphosphokinase, the mutant exhibits higher activity. When used in a genetically engineered Escherichia coli strain, this mutant catalyzes the synthesis of NMN (nicotinamide mononucleotide) from D-ribose, ATP, and nicotinamide, achieving a high yield of 25.2 g/L in 3 hours, demonstrating significant industrial potential for large-scale NMN production.

10 September 2024 | Pending

Product Tag:

Polyphosphokinase Mutant

Industry Tag:

Synthetic Biology

Method for producing PHA through semi-continuous fermentation

The invention provides a method for producing polyhydroxyalkanoate (PHA) via semi-continuous fermentation using Halomonas as a base strain, with the overexpression of the cell division protein gene ftsZ. This approach addresses the issues of reduced splitting activity and lower yield due to metabolic disturbances during long continuous fermentation, achieving high PHA yields in practical applications, and offering strong potential for industrial scalability.

28 August 2024 | Pending

Technology Tag:

Product Tag:

PHA

Industry Tag:

Packaging

Pectase-producing microbubble bacteria and application thereof.

The invention discloses a pectinase-producing strain, identified as Microvesicles MYHB-202306PeC, belonging to the Microvesicles genus. This strain is capable of high salt tolerance and the secretion of pectinase, which makes it useful in applications such as food processing, waste management, and other industrial uses requiring pectin degradation.

20 August 2024 | Pending

Technology Tag:

Product Tag:

Pectinase

Industry Tag:

Synthetic Biology

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