ACCELERATING. SYNTHETIC BIOLOGY. ADVANCEMENT

Backed by the Samsung Venture, this investment supports Generate’s AI-driven platform to address critical challenges in human health through advanced protein therapeutics.

Utilizing the EMP™ platform, Abilita will support Orion's drug discovery for multi-span membrane proteins, with potential earnings of up to $785M plus royalties.

Funded by ARPA-H's REACT initiative, the collaboration focuses on creating engineered cells to deliver therapeutic molecules and monitor disease status.

Led by GreyBird Ventures, the funding will enable NeuroKaire to scale its innovative approach to personalized drug efficacy and expand industry collaborations.

The invention provides a genetically engineered bacterium for producing sialylated human milk oligosaccharide by co-expressing a Sec signal peptide and sialyltransferase, enhancing the secretion and expression efficiency of the enzyme. This method improves the fermentation yield of sialylated human milk oligosaccharides through localized synthesis of intermediate and final products in the periplasmic space.

The invention relates to recombinant halophilic bacteria engineered to efficiently produce Taq DNA polymerase, which exhibits high yield, enhanced salt tolerance, DNA polymerase activity, and heat resistance, making it suitable for applications like PCR. The method provides a cost-effective, simple production process, allowing for open continuous fermentation without sterilization, and offers high production efficiency and broad application prospects.

The invention discloses a method for preparing triple-helix type III recombinant human collagen using yeast fermentation. This method involves constructing a high-expression engineered strain, introducing a P4H enzyme plasmid, and then obtaining the mature collagen by fermentation and purification. The resulting collagen contains hydroxyproline (over 40% of total proline) and is suitable for use in cosmetics, medical devices, and biomedical materials.

The invention describes a method to produce recombinant humanized collagen with a triple helix structure using yeast expression, incorporating P4H expression plasmids for enhanced hydroxyproline content. This collagen, which is suitable for use in cosmetics, medical devices, and biomedical materials, has hydroxyproline accounting for more than 30% of total proline.

This study investigates secretion bottlenecks in Bacillus subtilis enzyme production, identifying LonA protease as a key factor affecting yields of XynA and AmyM.

This review explores advances in fungal melanin biosynthesis, structure, and regulation, emphasizing their potential for engineered production and diverse applications.

This study demonstrates the potential of Marinobacter atlanticus biofilms for continuous wax ester production from succinate, paving the way for sustainable lipid synthesis in bioeconomy applications.

The research explores the formin gene family in G. raimondii, identifying their role in stress tolerance and lint production, with implications for improving cotton's resilience and quality.